What's New

January 2023

Say Hello to Willy!

Based on the circle of Willis, Willy hopes to raise awareness about the importance of transcranial Doppler ultrasound (TCD). Visit his page to learn more about the circle of Willis, the role of TCD, and how you can take part in the Where’s Willy Challenge. #whereswilly

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May 2022

Stroke Awareness Guide

May is stroke awareness month. Increasing awareness is an important step in the larger effort to eradicate neurological illnesses, diseases, and ailments. Download the guide to learn the important role transcranial Doppler plays in the diagnostic workup for a wide range of diseases affecting cerebral blood flow, including stroke.

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April 2022

NovaSignal’s Morphology Capability Provides New Insight to Physicians

As part of an exciting update to the NovaSignal Platform, we are pleased to announce to launch of Morphology. Morphology provides physicians with advanced analysis of cerebral waveforms to enable faster and easier assessment of patients with suspected neurological conditions, including stroke.

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February 2022

New Data Demonstrate NovaGuide™ Intelligent Ultrasound Significantly Improves Detection of Right-to-Left Shunt

Clinical trial results show NovaGuide™ is three times more likely to detect RLS than transthoracic echocardiography.

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December 2021

Clinical Impact: Perioperative Monitoring During TCAR Procedure

Every year nearly 800,000 people in the US have a stroke. Around 10 to 20 percent of strokes are due to carotid artery disease and more than 100,000 carotid revascularization procedures are performed every year. Without the help of cerebral blood flow monitoring, inadequate blood supply, dangerous embolization, and hyperperfusion can go unseen by the surgical team. Download the case to learn how the real-time blood flow data provided by the NovaSignal Platform allows clinicians to immediately respond to perioperative concerns.

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September 2021

TCD Offers Hope for Children with Sickle Cell Disease

More than 75% of the global burden of SCD occurs in sub-Saharan Africa, where an estimated 1.03 million children are afflicted. Learn more about how Dr. Nicole O’Brien and Nationwide Children’s Hospital is using TCD to help treat SCD in Africa!

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August 2021

New Enhancements to NovaSignal Platform Enable Remote Monitoring and Boost Telehealth Capabilities

With new live exam streaming capabilities, hospitals can expedite patient assessment and triage by quickly connecting patients with clinical specialists within the hospital or across the health system. Members of the clinical team can now remotely monitor vessel velocities and emboli count in real time, while automatic notifications on key events improve team coordination.

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July 2021

New Research - Cerebral Microembolic Signal Burden During Pulsed Filed Ablation: Preliminary Results from Robotically Assisted Transcranial Doppler

Transcranial Doppler (TCD) has been used to monitor the burden of cerebral microembolic signals (MESs) during atrial fibrillation (AF) ablation. MES burden is considered a surrogate marker for stroke risk and has never been reported during AF ablation with the novel pulsed field ablation (PFA) system.

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April 2021

Introducing the NovaSignal Platform

The NovaSignal Platform empowers clinical teams with critical information about cerebral blood flow to guide diagnosis and improve patient outcomes. Designed to seamlessly integrate into existing clinical practice, the platform includes the NovaGuide 2 Intelligent Ultrasound which autonomously captures blood flow data to identify brain illnesses and disease, and NovaGuide View which provides secure, cloud-based access to dynamic exam data.

October 2020

First Patient Enrolled in BUBL Clinical Trial

A PFO, more commonly known as a hole in the heart, is a congenital abnormality impacting approximately 25% of the entire population and is a known risk factor for stroke. Across the globe 500,000 strokes occur every year in patients suspected of having a PFO. The primary objective of the trial is to evaluate the PFO detection rate of NovaGuide vs standard of care diagnostic techniques. The BUBL trial is a prospective, single-arm, non-significant risk (NSR) device study. Up to 200 patients across six US sites with suspicion of embolic stroke of unknown origin will be evaluated with the NovaGuide and TTE. Want to learn more about the benefits of NovaGuide for PFO detection?

August 2020

NovaGuide Intelligent Ultrasound Uncovers Possible Breakthrough in Patients with COVID-19

Data published in the American Journal of Respiratory and Critical Care Medicine utilized the NovaGuide Intelligent Ultrasound to remotely assess and monitor patients with COVID-19. Critical care teams at Mount Sinai Health System used the company’s autonomous robotic ultrasound to monitor cerebral blood flow of 18 mechanically ventilated patients with COVID-19 and revealed insights into the pathophysiology of the virus. While monitoring these critically ill patients with NovaGuide, physicians discovered an overabundance of pulmonary shunting, a physical dysfunction whereby deoxygenated blood bypasses the normal circulatory system resulting in lower levels of oxygen in the blood and contributing to respiratory distress in patients with COVID-19.

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